Histopathological and clinical characteristics of duodenal gastrointestinal stromal tumors as predictors of malignancy
نویسندگان
چکیده
منابع مشابه
Histopathological and clinical characteristics of duodenal gastrointestinal stromal tumors as predictors of malignancy
BACKGROUND Although gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, they are very rare. This study evaluated clinical and histopathological characteristics of duodenal GISTs to identify factors useful in predicting prognosis for patients with these tumors. METHODS A retrospective study was performed on 20 patients who had undergone...
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Download pose: Gastrointestinal stromal tumors (GIST) are the most important mesenchymal tumors of the intestinal tract. The vast majority of GISTs exhibit activating mutations of KIT or PDGFRA, but epic alteration of GISTs is largely unknown. In this study, we aimed to clarify the involvement of DNA lation in GIST malignancy. erimental Design: A total of 106 GIST specimens were studied. Levels...
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Gastrointestinal stromal tumors (GISTs) originating in the duodenal wall constitute the most challenging localization for this gastrointestinal neoplasm. Duodenal GISTs are relatively uncommon. The prevalence of duodenal GIST is very low, accounting for 5% to 7% or less of all surgically resected GISTs. Most published reports on duodenal GIST are case reports or small case series. Consequently,...
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BACKGROUND This study evaluated the clinical characteristics, surgical procedures and prognosis of duodenal gastrointestinal stromal tumours (GISTs). METHODS Patients with a diagnosis of primary duodenal GIST treated between January 2000 and December 2012 were analysed. Patients with gastric and small intestinal GISTs were chosen as control groups according to the following parameters: age, t...
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Background: Gastrointestinal stromal tumors (GISTs) constitute the majority of gastrointestinal mesenchymal tumors. They usually express a proto-oncogen protein called CD117 detected by immunohistochemistry. This study investigated the differentiation of GISTs as well as the risk of aggressive behaviors in GISTs from surgically-treated patients in university affiliated hospitals. Methods: The c...
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ژورنال
عنوان ژورنال: World Journal of Surgical Oncology
سال: 2013
ISSN: 1477-7819
DOI: 10.1186/1477-7819-11-202